Undenatured Collagen versus Hydrolyzed Collagen Peptides

As evidence of the health benefits of collagen mounts, collagen supplements are growing in popularity. There are two forms of supplemental collagen with different mechanisms of action: Undenatured/Native Collagen and Hydrolyzed Collagen.

So, what’s the difference?

Undenatured collagen is the native form of collagen that’s extracted purely from the cartilage of hens to retain its bioactive triple helix shape. It’s this helical structure that supports joint health and flexibility. By introducing it to the body in small doses, undenatured type 2 collagen acts as an immune modulator, preventing the immune system from attacking the body’s joint cartilage. This allows room for strong, flexible joint cartilage to be renewed and rebuilt.

Hydrolyzed collagen (also known as collagen peptides and denatured collagen) is native collagen that’s been “digested” into small amino acid chains called peptides. The original collagen protein is put through enzymatic hydrolysis, breaking the bonds of the triple helix into small, bioavailable peptide building blocks. These peptides are rapidly absorbed by the body to be reassembled into collagen in connective tissue – whether that is type 1, type 2, type 3, or others!

These different collagen supplements also differ when it comes to dosage. Hydrolyzed collagen peptides need to be taken in larger doses, while undenatured collagen is only required in a small daily dose to exert its benefits. In short, undenatured collagen interacts with the immune system in the digestive tract, while hydrolyzed collagen promotes the synthesis of new collagen to help rebuild connective tissue.

At 10KATE Laboratories, we pride ourselves on being industry leaders when it comes to collagen supplements. Using our patented processing technology, we extract type 2 collagen in its native and biologically active form for use in our Carticol® formula.

Learn more about Collagen

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